Honor of Kings Mayene: Skill, Item Build, and Arcana Guide
Mayene is a versatile Fighter in Honor of Kings, excelling at damage output, mobility, and crowd control. She thrives in the Clash Lane, using her unique combo-based abilities to disrupt enemies, close gaps, and sustain herself in fights. With a well-timed combination of punches and kicks, she can deal burst damage, evade enemy attacks, and lock down key targets.
In this guide, we will cover her best skill combos, item build, arcana setup, spells, and gameplay strategies to help you master Mayene and dominate the battlefield.
Mayene

Hero Information
Class | Fighter |
Lane Role | Clash Lane |
Popularity | C |
Win Rate | 47.72% |
Pick Rate | 0.67% |
Ban Rate | 0.05% |
Mayene’s Skills & Effects
Passive: Slack Off a Lil Bit (Self-Sustain & Strength Recovery)
- Mayene has two resource bars:
- Punch Strength (used for certain attacks).
- Kick Strength (used for movement and defensive skills).
- When idle (not attacking, moving, or taking damage), she sits down and:
- Recovers Strength 25% faster.
- Heals 80 (+20% Physical Attack) HP per second.
- Slacking off stops when she moves, attacks, or enters Serious State.
🡆 Tips:
✔ Use downtime efficiently – If safe, let her recover Strength before re-engaging.
✔ Self-healing lets her stay in fights longer without needing lifesteal items.
Skill 1-1: Whatever (I) (Gap Closer & Crowd Control)
- Mayene dashes forward, pulling in enemies.
- Deals 200 (+80% Physical Attack) physical damage.
- Slows targets by 30% for 1.5 seconds.
- Costs 1 Punch Strength bar (max 2 stored).
🡆 Tips:
✔ Great for engaging or chasing fleeing enemies.
✔ Use to disrupt enemy formations in team fights.
Skill 1-2: Exploit Weakness (Follow-Up Attack & Knock-Up CC)
- Combo attack after Skill 1-1:
- Leaps into the air and slams down on enemies.
- Deals 8% of the target’s max HP + 250 (+115% Physical Attack) damage.
- Enemies at the center take 50% extra damage.
- Mayene takes 30% reduced damage while casting.
🡆 Tips:
✔ Aim for the center of the attack for bonus damage.
✔ Use defensively to reduce damage taken in fights.
Skill 1-3: Defend by Attacking (Finisher Move & Healing Sustain)
- Final hit of her 1-1 combo:
- Teleports behind an enemy and delivers a spinning kick.
- Deals 250 (+100% Physical Attack) (+18% of target’s lost HP) physical damage.
- Knocks back the enemy.
- If the enemy dies, she heals 100 (+60% Physical Attack) HP and regains 50% Strength.
🡆 Tips:
✔ Best used as a finisher move when an enemy is low.
✔ Can be used to reposition or escape from danger.
Skill 2-1: Whatever (II) (Dodge & Damage Reduction)
- Flips forward, evading enemy attacks.
- Grants CC immunity while moving.
- 30% damage reduction.
- Heals 50 (+60% Physical Attack) HP.
- Costs 1 Kick Strength bar (max 2 stored).
🡆 Tips:
✔ Use to dodge enemy skill shots or crowd control abilities.
✔ Useful for quick repositioning in fights.
Skill 2-2: Feint to Retreat (Multi-Hit Combo & Knockback)
- Follow-up attack after Skill 2-1:
- Delivers 3 fast punches (150 + 50% Physical Attack damage each).
- Finishes with a knee strike (8% target’s max HP damage).
- Heals 50 (+60% Physical Attack) HP.
🡆 Tips:
✔ Use for sustained DPS in direct combat.
✔ Follow up with Skill 1-1 for additional CC and burst damage.
Ultimate: Get Serious (Power-Up Mode & Burst Damage)
- Deals 300 (+80% Physical Attack) AoE damage.
- Enters Serious State for 10s:
- Punch/Kick Strength bars increase to 3 each.
- Gains 20% Movement Speed.
- Slows inflicted on her are reduced by 50%.
🡆 Tips:
✔ Activate before engaging for full power.
✔ Gives more combo potential with increased Strength bars.
Best Skill Combos for Mayene
🔹 Gank Combo (High Damage & CC)
🡆 3 → 2-2 → 1-1 → 3 → 2-3 → 1-3
✔ Great for ambushes and securing kills.
🔹 Team Fight Combo (Mobility & Burst Damage)
🡆 2-2 → 3 → 3 → 1-1 → 2-1 → 3 → 2-3
✔ Maximizes damage while dodging enemy abilities.
Best Item Build for Mayene
1️⃣ Boots of Fortitude – Movement Speed + Physical Defense.
2️⃣ Axe of Torment – Cooldown Reduction + Physical Pierce.
3️⃣ Pure Sky – Active Ability: Gain 35% Damage Reduction for 3s.
4️⃣ Cuirass of Savagery – Boosts Attack + HP.
5️⃣ Eye of the Phoenix – Magical Defense + HP Regen.
6️⃣ Starbreaker – Physical Attack + Armor Pierce.
Best Spells for Mayene
✔ Flash – Escape tool or initiation.
✔ Execute – Secures kills on low-health enemies.
Best Arcana for Mayene
🔥 Mutation – Boosts attack damage & penetration.
⚡ Stealth – Increases Movement Speed & Attack Power.
🏹 Eagle Eye – Enhances physical attack & armor penetration.
Master Mayene & Dominate Fights!
By following this detailed guide, you’ll be able to maximize Mayene’s damage, survivability, and team fight presence. She is an exceptional duelist, and with the right skill combos, items, and Arcana, you can carry games and lead your team to victory!
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